Furylfuramide isomerase

From Wikipedia, the free encyclopedia

In enzymology, a furylfuramide isomerase (EC 5.2.1.6) is an enzyme that catalyzes the chemical reaction

(E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide

Hence, this enzyme has one substrate, (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, and one product, (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase. It has 2 cofactors: NAD+, and NADH.

[edit] References

• IUBMB entry for 5.2.1.6
• BRENDA references for 5.2.1.6 (Recommended.)
• PubMed references for 5.2.1.6
• PubMed Central references for 5.2.1.6
• Google Scholar references for 5.2.1.6
• Tomoeda M, Kitamura R (1977). "A cis-trans isomerising activity of Escherichia coli. Isomerization from 2-(2-furyl)-3-cis-(5-nitro-2-furyl) acrylamide (furylfuramide) to its trans isomer". Biochim. Biophys. Acta. 480: 315–25. PMID 12827. 

[edit] External links

The CAS registry number for this enzyme class is 72561-07-0.

• IUBMB entry for 5.2.1.6

• KEGG entry for 5.2.1.6

• BRENDA entry for 5.2.1.6

• NiceZyme view of 5.2.1.6

• EC2PDB: PDB structures for 5.2.1.6

• PRIAM entry for 5.2.1.6

• PUMA2 entry for 5.2.1.6

• IntEnz: Integrated Enzyme entry for 5.2.1.6

• MetaCyc entry for 5.2.1.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047907: furylfuramide isomerase

• AMIGO entry for GO code 0047907: furylfuramide isomerase