Furanolactone

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The chemical structure of salvinorin A
The chemical structure of salvinorin A

A furanolactone is a heterocyclic chemical compound that contains both a lactone and a furan ring structure. Examples include the hallucinogenic compound salvinorin A and the potential chemopreventive compound columbin.

[edit] References

  1. Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Dersch CM, Rothman RB, Prisinzano TE. (2006). Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring. Bioorg Med Chem Lett 16(12):3170-4.
  2. Kohno H, Maeda M, Tanino M, Tsukio Y, Ueda N, Wada K, Sugie S, Mori H, Tanaka T. (2002). A bitter diterpenoid furanolactone columbin from Calumbae Radix inhibits azoxymethane-induced rat colon carcinogenesis. Cancer Lett 183(2):131-9.
  3. Swaminathan K, Sinha UC, Ramakumar S, Bhatt RK, Sabata BK. (1989). Structure of columbin, a diterpenoid furanolactone from Tinospora cordifolia Miers. Acta Crystallogr C 45 ( Pt 2):300-3.


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