Fumarate reductase (NADH)

From Wikipedia, the free encyclopedia

In enzymology, a fumarate reductase (NADH) (EC 1.3.1.6) is an enzyme that catalyzes the chemical reaction

succinate + NAD⁺ fumarate + NADH + H⁺

Thus, the two substrates of this enzyme are succinate and NAD⁺, whereas its 3 products are fumarate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is succinate:NAD+ oxidoreductase. Other names in common use include NADH-fumarate reductase, NADH-dependent fumarate reductase, and fumarate reductase (NADH).

[edit] References

• IUBMB entry for 1.3.1.6
• BRENDA references for 1.3.1.6 (Recommended.)
• PubMed references for 1.3.1.6
• PubMed Central references for 1.3.1.6
• Google Scholar references for 1.3.1.6
• Hopgood MF and Walker DJ (1969). "Succinic acid production by rumen bacteria. III. Enzymic studies on the formation of succinate by Ruminococcus flavefaciens". Aust. J. Biol. Sci. 22: 1413–1424. 

[edit] External links

The CAS registry number for this enzyme class is 9076-99-7.

• IUBMB entry for 1.3.1.6

• KEGG entry for 1.3.1.6

• BRENDA entry for 1.3.1.6

• NiceZyme view of 1.3.1.6

• EC2PDB: PDB structures for 1.3.1.6

• PRIAM entry for 1.3.1.6

• PUMA2 entry for 1.3.1.6

• IntEnz: Integrated Enzyme entry for 1.3.1.6

• MetaCyc entry for 1.3.1.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0016156: fumarate reductase (NADH)

• AMIGO entry for GO code 0016156: fumarate reductase (NADH)