FUCA2

From Wikipedia, the free encyclopedia

Fucosidase, alpha-L- 2, plasma

Identifiers

FUCA2; MGC1314; RP1-20N2.5; dJ20N2.5

External IDs

OMIM: 136820 MGI: 1914098 HomoloGene: 119

Gene ontology
Molecular Function:	• catalytic activity • alpha-L-fucosidase activity • hydrolase activity, acting on glycosyl bonds • cation binding
Biological Process:	• carbohydrate metabolic process • metabolic process

Orthologs

Human

Mouse

Refseq

NM_032020 (mRNA)
NP_114409 (protein)

NM_025799 (mRNA)
NP_080075 (protein)

Location

Chr 6: 143.86 - 143.87 Mb

Chr 10: 13.19 - 13.21 Mb

Pubmed search

[1]

[2]

Fucosidase, alpha-L- 2, plasma, also known as FUCA2, is a human gene.^[1]

[edit] References

^ Entrez Gene: FUCA2 fucosidase, alpha-L- 2, plasma.

[edit] Further reading

Narahara K, Tsuji K, Yokoyama Y, et al. (1991). "Specification of small distal 6q deletions in two patients by gene dosage and in situ hybridization study of plasminogen and alpha-L-fucosidase 2.". Am. J. Med. Genet. 40 (3): 348-53. doi:10.1002/ajmg.1320400322. PMID 1951444.
O'Brien JS, Willems PJ, Fukushima H, et al. (1988). "Molecular biology of the alpha-L-fucosidase gene and fucosidosis.". Enzyme 38 (1-4): 45-53. PMID 2894306.
Eiberg H, Mohr J, Nielsen LS (1984). "Linkage of plasma alpha-L-fucosidase (FUCA2) and the plasminogen (PLG) system.". Clin. Genet. 26 (1): 23-9. PMID 6590153.
Cordero OJ, Merino A, Páez de la Cadena M, et al. (2001). "Cell surface human alpha-L-fucosidase.". Eur. J. Biochem. 268 (11): 3321-31. PMID 11389735.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743.