Free fraction
From Wikipedia, the free encyclopedia
 |
This article or section is in need of attention from an expert on the subject. Please help recruit one or improve this article yourself. See the talk page for details. Please consider using {{Expert-subject}} to associate this request with a WikiProject |
The free fraction is a parameter in pharmacokinetics and receptor-ligand kinetics. One speaks of two different free fractions:
- Plasma free fraction, previously referred to as f1,[1] is now referred to as fP according to consensus nomenclature.[2]
- Tissue free fraction, previously referred to as f2[1]
[edit] See also
[edit] References
- ^ a b Roger N. Gunn, Steve R. Gunn, Federico E. Turkheimer, John A. D. Aston and Vincent J. Cunningham (2002). "Positron Emission Tomography Compartmental Models: A Basis Pursuit Strategy for Kinetic Modeling". J. Cereb. Blood Metab. 22 (4): 1425–1439. doi:.Table
- ^ Innis et al (2007). "Consensus nomenclature for in vivo imaging of reversibly binding radioligands". J. Cereb Blood Flow and Metab. 27 (9): 1533–1539. doi:.
[edit] Others
- Milak MS, Severance AJ, Ogden RT, Prabhakaran J, Kumar JS, Majo VJ, Mann JJ, Parsey RV (2008). "Modeling Considerations for 11C-CUMI-101, an Agonist Radiotracer for Imaging Serotonin 1A Receptor In Vivo with PET". J. Nucl. Med. 49 (4): 587–596. doi:. PMID 18344443.
 |
This biochemistry article is a stub. You can help Wikipedia by expanding it. |
