Framycetin

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Framycetin
Systematic (IUPAC) name
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl) -6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R) -4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl) -4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy -5-(hydroxymethyl)oxolan-2-yl]oxy -3-hydroxycyclohexyl]oxyoxane-3,4-diol
Identifiers
CAS number	?
ATC code	R01AX08
PubChem	8378
Chemical data
Formula	C23H46N6O13
Mol. mass	614.644 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	oral, topical

Framycetin is an antibiotic of the aminoglycoside class similar to neomycin. Like neomycin, it has poor systemic absorption. It is used in topical preparations for infections of the skin, nose, ears, and eyes, often in combination with other antibacterial drugs and corticosteroids. It can also be used for gastrointestinal infections.

Framycetin is commonly sold as Soframycin and Sofra-Tulle.

v • d • e Decongestants and other nasal preparations (R01) Topical: sympathomimetics, plain Cyclopentamine - Ephedrine - Phenylephrine - Oxymetazoline - Tetryzoline - Xylometazoline - Naphazoline - Tramazoline - Metizoline - Tuaminoheptane - Fenoxazoline - Tymazoline - Epinephrine Topical: antiallergic agents, excluding corticosteroids Cromoglicic acid - Levocabastine - Azelastine - Antazoline - Spaglumic acid - Thonzylamine - Nedocromil - Olopatadine Topical: corticosteroids Beclometasone - Prednisolone - Dexamethasone - Flunisolide - Budesonide - Betamethasone - Tixocortol - Fluticasone - Mometasone furoate - Triamcinolone - Ciclesonide Topical: other nasal preparations Calcium hexamine thiocyanate - Retinol - Ipratropium bromide - Ritiometan - Mupirocin - Hexamidine - Framycetin Systemic use: Sympathomimetics Phenylpropanolamine - Pseudoephedrine - Phenylephrine

v • d • e Antibacterials for systemic use: aminoglycosides (J01G) -mycin (Streptomyces) Streptomycin • Neomycin (Framycetin, Paromomycin, Ribostamycin) • Kanamycin (Amikacin, Dibekacin, Tobramycin) • Hygromycin B • Spectinomycin -micin (Micromonospora) Gentamicin (Netilmicin, Sisomicin, Isepamicin) • Verdamicin