Fosmidomycin
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Fosmidomycin
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Systematic (IUPAC) name | |
3-[Formyl(hydroxy)amino]propoylphosphonic acid | |
Identifiers | |
CAS number | |
ATC code | ? |
PubChem | |
DrugBank | |
Chemical data | |
Formula | C4H10NO5P |
Mol. mass | 183.100 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
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Legal status | |
Routes | ? |
Fosmidomycin is an antibiotic that specific inhibits DXP reductoisomerase, a key enzyme in the non-mevalonate pathway. It is a structural analogue of 2-C-methyl-D-erythrose 4-phosphate. It inhibits the E. coli enzyme with a KI value of 38 nM (4).