Formylmethanofuran dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a formylmethanofuran dehydrogenase (EC 1.2.99.5) is an enzyme that catalyzes the chemical reaction

formylmethanofuran + H₂O + acceptor CO₂ + methanofuran + reduced acceptor

The 3 substrates of this enzyme are formylmethanofuran, H₂O, and acceptor, whereas its 3 products are CO₂, methanofuran, and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with other acceptors. The systematic name of this enzyme class is formylmethanofuran:acceptor oxidoreductase. This enzyme is also called formylmethanofuran:(acceptor) oxidoreductase. This enzyme participates in folate biosynthesis. It has 2 cofactors: molybdenum, and Pterin.

[edit] References

• IUBMB entry for 1.2.99.5
• BRENDA references for 1.2.99.5 (Recommended.)
• PubMed references for 1.2.99.5
• PubMed Central references for 1.2.99.5
• Google Scholar references for 1.2.99.5
• Karrasch M, Borner G, Enssle M, Thauer RK (1990). "The molybdoenzyme formylmethanofuran dehydrogenase from Methanosarcina barkeri contains a pterin cofactor". Eur. J. Biochem. 194: 367–72. doi:10.1111/j.1432-1033.1990.tb15627.x. PMID 2125267. 

[edit] External links

The CAS registry number for this enzyme class is 119940-12-4.

• IUBMB entry for 1.2.99.5

• KEGG entry for 1.2.99.5

• BRENDA entry for 1.2.99.5

• NiceZyme view of 1.2.99.5

• EC2PDB: PDB structures for 1.2.99.5

• PRIAM entry for 1.2.99.5

• PUMA2 entry for 1.2.99.5

• IntEnz: Integrated Enzyme entry for 1.2.99.5

• MetaCyc entry for 1.2.99.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018493: formylmethanofuran dehydrogenase

• AMIGO entry for GO code 0018493: formylmethanofuran dehydrogenase