Formylation reaction
From Wikipedia, the free encyclopedia
A Formylation reaction in organic chemistry is the catch-all name for any organic reaction in which an organic compound is functionalized with a formyl group -CH=O.
Aromatic formylations exist with:
- dimethylformamide and phosphorus oxychloride in the Vilsmeier-Haack reaction
- hexamine in the Duff reaction and the Sommelet reaction
- carbon monoxide and hydrochloric acid in the Gattermann-Koch reaction
- zinc cyanide and hydrochloric acid in the Gatterman Aldehyde Synthesis
- chloroform in the Reimer-Tiemann reaction
These reactions are all electrophilic aromatic substitutions
