Formyl-CoA hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a formyl-CoA hydrolase (EC 3.1.2.10) is an enzyme that catalyzes the chemical reaction

formyl-CoA + H₂O CoA + formate

Thus, the two substrates of this enzyme are formyl-CoA and H₂O, whereas its two products are CoA and formate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is formyl-CoA hydrolase. This enzyme is also called formyl coenzyme A hydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

[edit] References

• IUBMB entry for 3.1.2.10
• BRENDA references for 3.1.2.10 (Recommended.)
• PubMed references for 3.1.2.10
• PubMed Central references for 3.1.2.10
• Google Scholar references for 3.1.2.10
• Sly WS and Stadtman ER (1963). "Formate metabolism. I. Formyl coenzyme A, an intermediate in the formate-dependent decomposition of acetyl phosphate in Clostridium kluyveri". J. Biol. Chem. 238: 2632–2638. 

[edit] External links

The CAS registry number for this enzyme class is 9025-91-6.

• IUBMB entry for 3.1.2.10

• KEGG entry for 3.1.2.10

• BRENDA entry for 3.1.2.10

• NiceZyme view of 3.1.2.10

• EC2PDB: PDB structures for 3.1.2.10

• PRIAM entry for 3.1.2.10

• PUMA2 entry for 3.1.2.10

• IntEnz: Integrated Enzyme entry for 3.1.2.10

• MetaCyc entry for 3.1.2.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047901: formyl-CoA hydrolase

• AMIGO entry for GO code 0047901: formyl-CoA hydrolase