Formimidoylglutamate deiminase

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In enzymology, a formimidoylglutamate deiminase (EC 3.5.3.13) is an enzyme that catalyzes the chemical reaction

N-formimidoyl-L-glutamate + H₂O N-formyl-L-glutamate + NH₃

Thus, the two substrates of this enzyme are N-formimidoyl-L-glutamate and H₂O, whereas its two products are N-formyl-L-glutamate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N-formimidoyl-L-glutamate iminohydrolase. Other names in common use include formiminoglutamate deiminase, and formiminoglutamic iminohydrolase. This enzyme participates in histidine metabolism.

[edit] References

• IUBMB entry for 3.5.3.13
• BRENDA references for 3.5.3.13 (Recommended.)
• PubMed references for 3.5.3.13
• PubMed Central references for 3.5.3.13
• Google Scholar references for 3.5.3.13
• Wickner RB and Tabor H (1971). "N-Formimino-L-glutamate iminohydrolase (Pseudomonas sp.)". Methods Enzymol. 17B: 80–84. 

[edit] External links

The CAS registry number for this enzyme class is 9054-85-7.

• IUBMB entry for 3.5.3.13

• KEGG entry for 3.5.3.13

• BRENDA entry for 3.5.3.13

• NiceZyme view of 3.5.3.13

• EC2PDB: PDB structures for 3.5.3.13

• PRIAM entry for 3.5.3.13

• PUMA2 entry for 3.5.3.13

• IntEnz: Integrated Enzyme entry for 3.5.3.13

• MetaCyc entry for 3.5.3.13

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050416: formimidoylglutamate deiminase

• AMIGO entry for GO code 0050416: formimidoylglutamate deiminase