Florfenicol
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Florfenicol
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| Systematic (IUPAC) name | |
| 2,2-dichloro-N-((1R,2S)-3-fluoro-1- hydroxy-1-(4-(methylsulfonyl) phenyl) propan-2-yl) ethanamide | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C12H14Cl2FNO4S |
| Mol. mass | 358.21 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
veterinary prescription only |
| Routes | intramuscular, subcutaneous |
Florfenicol (marketed by Schering-Plough Animal Health under the trade name Nuflor) is a fluorinated synthetic analog of thiamphenicol.[1]
In the United States, florfenicol is currently indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Haemophilus somnus. For treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.
[edit] External links
[edit] References
- ^ Syriopoulou VP, Harding AL, Goldmann DA, Smith AL (Feb 1981). "In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol.". Antimicrob Agents Chemother. 19 (2): 294–7. PMID 6957162.
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