Flavonol 3-O-glucosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a flavonol 3-O-glucosyltransferase (EC 2.4.1.91) is an enzyme that catalyzes the chemical reaction

UDP-glucose + a flavonol $\rightleftharpoons$ UDP + a flavonol 3-O-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and flavonol, whereas its two products are UDP and flavonol 3-O-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol 3-O-D-glucosyltransferase. Other names in common use include GTI, uridine diphosphoglucose-flavonol 3-O-glucosyltransferase, UDP-glucose:flavonol 3-O-glucosyltransferase, and UDPG:flavonoid-3-O-glucosyltransferase. This enzyme participates in flavonoid biosynthesis.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2C1X, 2C1Z, and 2C9Z.

[edit] References

IUBMB entry for 2.4.1.91
BRENDA references for 2.4.1.91 (Recommended.)
PubMed references for 2.4.1.91
PubMed Central references for 2.4.1.91
Google Scholar references for 2.4.1.91
Wiermann R (1982). "Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development". Z. Natursforsch. C: Biosci. 37: 587–599.
Sutter A, Grisebach H (1973). "UDP-glucose: flavonol 3-0-glucosyltransferase from cell suspension cultures of parsley". Biochim. Biophys. Acta. 309: 289–95. PMID 4731963.