Flavone 7-O-beta-glucosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a flavone 7-O-beta-glucosyltransferase (EC 2.4.1.81) is an enzyme that catalyzes the chemical reaction

UDP-glucose + 5,7,3',4'-tetrahydroxyflavone $\rightleftharpoons$ UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone

Thus, the two substrates of this enzyme are UDP-glucose and 5,7,3',4'-tetrahydroxyflavone, whereas its two products are UDP and 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase. Other names in common use include UDP-glucose-apigenin beta-glucosyltransferase, UDP-glucose-luteolin beta-D-glucosyltransferase, uridine diphosphoglucose-luteolin glucosyltransferase, uridine diphosphoglucose-apigenin 7-O-glucosyltransferase, and UDP-glucosyltransferase. This enzyme participates in flavonoid biosynthesis.

[edit] References

IUBMB entry for 2.4.1.81
BRENDA references for 2.4.1.81 (Recommended.)
PubMed references for 2.4.1.81
PubMed Central references for 2.4.1.81
Google Scholar references for 2.4.1.81
Sutter A, Ortmann R, Grisebach H (1972). "Purification and properties of an enzyme from cell suspension cultures of parsley catalyzing the transfer of D-glucose from UDP-D-glucose to flavonoids". Biochim. Biophys. Acta. 258: 71–87. PMID 5058406.