FIP1L1

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FIP1 like 1 (S. cerevisiae)
Identifiers
Symbol(s) FIP1L1; DKFZp586K0717; FLJ33619; Rhe
External IDs OMIM: 607686 MGI: 1914149 HomoloGene: 23439
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 81608 66899
Ensembl ENSG00000145216 ENSMUSG00000029227
Uniprot Q6UN15 n/a
Refseq NM_030917 (mRNA)
NP_112179 (protein)		 NM_024183 (mRNA)
NP_077145 (protein)
Location Chr 4: 53.94 - 54.02 Mb Chr 5: 74.82 - 74.88 Mb
Pubmed search [1] [2]

FIP1 like 1 (S. cerevisiae), also known as FIP1L1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: FIP1L1 FIP1 like 1 (S. cerevisiae).

[edit] Further reading

  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788-95. PMID 11076863. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Cools J, DeAngelo DJ, Gotlib J, et al. (2003). "A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.". N. Engl. J. Med. 348 (13): 1201-14. doi:10.1056/NEJMoa025217. PMID 12660384. 
  • Griffin JH, Leung J, Bruner RJ, et al. (2003). "Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome.". Proc. Natl. Acad. Sci. U.S.A. 100 (13): 7830-5. doi:10.1073/pnas.0932698100. PMID 12808148. 
  • Pardanani A, Ketterling RP, Brockman SR, et al. (2004). "CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.". Blood 102 (9): 3093-6. doi:10.1182/blood-2003-05-1627. PMID 12842979. 
  • Cools J, Quentmeier H, Huntly BJ, et al. (2004). "The EOL-1 cell line as an in vitro model for the study of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.". Blood 103 (7): 2802-5. doi:10.1182/blood-2003-07-2479. PMID 14630792. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Sakashita E, Tatsumi S, Werner D, et al. (2004). "Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo.". Mol. Cell. Biol. 24 (3): 1174-87. PMID 14729963. 
  • Kaufmann I, Martin G, Friedlein A, et al. (2005). "Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.". EMBO J. 23 (3): 616-26. doi:10.1038/sj.emboj.7600070. PMID 14749727. 
  • Pardanani A, Brockman SR, Paternoster SF, et al. (2004). "FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia.". Blood 104 (10): 3038-45. doi:10.1182/blood-2004-03-0787. PMID 15284118. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136-44. doi:10.1101/gr.2576704. PMID 15489336. 
  • Zhao X, Oberg D, Rush M, et al. (2005). "A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein.". J. Virol. 79 (7): 4270-88. doi:10.1128/JVI.79.7.4270-4288.2005. PMID 15767428. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMID 16381901. 
  • Cools J, Stover EH, Gilliland DG (2006). "Detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia.". Methods Mol. Med. 125: 177-87. PMID 16502585. 
  • Stover EH, Chen J, Folens C, et al. (2006). "Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.". Proc. Natl. Acad. Sci. U.S.A. 103 (21): 8078-83. doi:10.1073/pnas.0601192103. PMID 16690743. 
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285-92. doi:10.1038/nbt1240. PMID 16964243. 
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