FightAIDS@Home
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FightAIDS@Home ("Fight AIDS at home") is a distributed computing project for internet-connected home computers, operated by the Olson Laboratory at The Scripps Research Institute. It aims to use biomedical software simulation techniques to search for ways to cure or prevent the spread of AIDS and HIV.
It was originally implemented using a distributed computing software infrastructure provided by Entropia. However, since May 2003 FightAIDS@Home has not been associated with Entropia,[1] and on November 21, 2005 the project moved to World Community Grid and the Entropia software was abandoned.[2]
FightAIDS@Home makes use of the AutoDock UD agent software, which tests how well a particular molecule binds to the HIV-1 protease. The minimum system requirements to run FightAIDS@home are:[3]
| Processor | 550 MHz |
|---|---|
| Memory | 250 MB |
| Hard drive | 600 MB (50 MB free) |
| Screen resolution | 8-bit graphics at 800x600 |
| Internet connection | 40 kbit/s |
Scripps Research Institute published its first peer-reviewed scientific paper about the results of FightAIDS@Home on April 21, 2007.[4] This paper explains that the results up to that point will primarily be used to improve the efficiency of future FightAIDS@Home calculations.[5]
[edit] Publications
Chang, Max W.; Lindstrom, William; Olson, Arthur J. & Belew, Richard K., “Analysis of HIV Wild-Type and Mutant Structures via in Silico Docking against Diverse Ligand Libraries”, J. Chem. Inf. Model. 47 (3): 1258 - 1262, doi:10.1021/ci700044s, <http://pubs.acs.org/cgi-bin/sample.cgi/jcisd8/2007/47/i03/pdf/ci700044s.pdf>
[edit] See also
[edit] References
- ^ Worthy Cause: Fight AIDS At Home Computer Project. FuturePundit (2003-12-01). Retrieved on 2007-08-08.
- ^ FightAIDS@Home. The Scripps Research Institute. Retrieved on 2007-08-08.
- ^ System Requirements. Help. World Community Grid. Retrieved on 2007-08-08.
- ^ Chang, Max W.; William Lindstrom, Arthur J. Olson, and Richard K. Belew (2007-04-21). Analysis of HIV Wild-Type and Mutant Structures via in Silico Docking against Diverse Ligand Libraries. J. Chem. Inf. Model. American Chemical Society. DOI:10.1021/ci700044s. Retrieved on 2007-07-30.
- ^ FightAIDS@Home News Volume 3. The Scripps Research Institute (2007-05-10). Retrieved on 2007-07-30.
[edit] External links
- World Community Grid - Research - FightAIDS@Home
- FightAIDS@Home at Scripps
- World Community Grid Targets AIDS in Giant Research Effort
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