Fiber diffraction

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Fiber diffraction is a scattering technique in which molecular structure is determined from scattering data (usually of X-rays or electrons) from filaments composed of a regular array of molecules distinguished by a single direction (the fiber axis). The resulting diffraction patterns show layer lines, each with Bessel function intensities.

[edit] Historical role

Fiber diffraction data led to several important advances in the development of structural biology, e.g., the original models of the α-helix and the Watson-Crick model of double-stranded DNA.

[edit] References

• Cochran W, Crick FHC, and Vand V (1952). "The Structure of Synthetic Polypeptides. I. The Transform of Atoms on a Helix". Acta Cryst., 5, 581-586.

[edit] External links

• Fiber Diffraction — an introduction provided by Prof. K.C. Holmes, Max Planck Institute for Medical Research, Heidelberg.

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