Phytochromobilin:ferredoxin oxidoreductase

From Wikipedia, the free encyclopedia

In enzymology, a phytochromobilin:ferredoxin oxidoreductase (EC 1.3.7.4) is an enzyme that catalyzes the chemical reaction

(3Z)-phytochromobilin + oxidized ferredoxin $\rightleftharpoons$ biliverdin IXalpha + reduced ferredoxin

Thus, the two substrates of this enzyme are (3Z)-phytochromobilin and oxidized ferredoxin, whereas its two products are biliverdin IXalpha and reduced ferredoxin.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is (3Z)-phytochromobilin:ferredoxin oxidoreductase. Other names in common use include HY2, PPhiB synthase, and phytochromobilin synthase. This enzyme participates in porphyrin and chlorophyll metabolism.

[edit] References

IUBMB entry for 1.3.7.4
BRENDA references for 1.3.7.4 (Recommended.)
PubMed references for 1.3.7.4
PubMed Central references for 1.3.7.4
Google Scholar references for 1.3.7.4
Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC (2001). "Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms". Plant. Cell. 13: 965–78. PMID 11283349.
McDowell MT, Lagarias JC (2001). "Purification and biochemical properties of phytochromobilin synthase from etiolated oat seedlings". Plant. Physiol. 126: 1546–54. PMID 11500553.
Terry MJ, Wahleithner JA, Lagarias JC (1993). "Biosynthesis of the plant photoreceptor phytochrome". Arch. Biochem. Biophys. 306: 1–15. PMID 8215388.