Ferric-chelate reductase

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In enzymology, a ferric-chelate reductase (EC 1.16.1.7) is an enzyme that catalyzes the chemical reaction

2 Fe(II) + NAD⁺ $\rightleftharpoons$ 2 Fe(III) + NADH + H⁺

Thus, the two substrates of this enzyme are Fe(II) and NAD⁺, whereas its 3 products are Fe(III), NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those oxidizing metal ion with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is Fe(II):NAD+ oxidoreductase. Other names in common use include ferric chelate reductase, iron chelate reductase, NADH:Fe3+-EDTA reductase, and NADH2:Fe3+ oxidoreductase.

[edit] References

IUBMB entry for 1.16.1.7
BRENDA references for 1.16.1.7 (Recommended.)
PubMed references for 1.16.1.7
PubMed Central references for 1.16.1.7
Google Scholar references for 1.16.1.7
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