Ferredoxin hydrogenase

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In enzymology, a ferredoxin hydrogenase (EC 1.12.7.2) is an enzyme that catalyzes the chemical reaction

H₂ + 2 oxidized ferredoxin $\rightleftharpoons$ 2 reduced ferredoxin + 2 H⁺

Thus, the two substrates of this enzyme are H₂ and oxidized ferredoxin, whereas its two products are reduced ferredoxin and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is hydrogen:ferredoxin oxidoreductase. Other names in common use include H2 oxidizing hydrogenase, H2 producing hydrogenase [ambiguous], bidirectional hydrogenase, hydrogen-lyase [ambiguous], hydrogenase (ferredoxin), hydrogenase I, hydrogenase II, hydrogenlyase [ambiguous], and uptake hydrogenase [ambiguous]. This enzyme participates in glyoxylate and dicarboxylate metabolism and methane metabolism. It has 3 cofactors: iron, Sulfur, and Nickel.

[edit] References

IUBMB entry for 1.12.7.2
BRENDA references for 1.12.7.2 (Recommended.)
PubMed references for 1.12.7.2
PubMed Central references for 1.12.7.2
Google Scholar references for 1.12.7.2
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