Ferredoxin-nitrite reductase

From Wikipedia, the free encyclopedia

In enzymology, a ferredoxin---nitrite reductase (EC 1.7.7.1) is an enzyme that catalyzes the chemical reaction

NH₃ + 2 H₂O + 6 oxidized ferredoxin $\rightleftharpoons$ nitrite + 6 reduced ferredoxin + 7 H⁺

The 3 substrates of this enzyme are NH₃, H₂O, and oxidized ferredoxin, whereas its 3 products are nitrite, reduced ferredoxin, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is ammonia:ferredoxin oxidoreductase. This enzyme participates in nitrogen metabolism. It has 3 cofactors: iron, Siroheme, and Iron-sulfur.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1ZJ8, 1ZJ9, and 2AKJ.

[edit] References

IUBMB entry for 1.7.7.1
BRENDA references for 1.7.7.1 (Recommended.)
PubMed references for 1.7.7.1
PubMed Central references for 1.7.7.1
Google Scholar references for 1.7.7.1
Joy KW, Hageman RH (1966). "The purification and properties of nitrite reductase from higher plants, and its dependence on ferredoxin". Biochem. J. 100: 263–73. PMID 4381617.
Ramirez JM, Del Campo FF, Paneque A, Losada M (1966). "Ferredoxin-nitrite reductase from spinach". Biochim. Biophys. Acta. 118: 58–71. PMID 5954064.
Zumft WG, Paneque A, Aparicio PJ, Losada M (1969). "Mechanism of nitrate reduction in Chlorella". Biochem. Biophys. Res. Commun. 36: 980–6. PMID 4390523.