FCRL2

From Wikipedia, the free encyclopedia

Fc receptor-like 2

Identifiers

FCRL2; SPAP1; FCRH2; IFGP4; IRTA4; SPAP1A; SPAP1B; SPAP1C

External IDs

Gene ontology
Molecular Function:	• receptor activity • SH3/SH2 adaptor activity
Cellular Component:	• soluble fraction • membrane • integral to membrane
Biological Process:	• cell-cell signaling

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

n/a

Refseq

NM_030764 (mRNA)
NP_110391 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 1: 155.98 - 156.01 Mb

n/a

Pubmed search

[1]

n/a

Fc receptor-like 2, also known as FCRL2, is a human gene.^[1]

[edit] References

^ Entrez Gene: FCRL2 Fc receptor-like 2.

[edit] Further reading

Xu MJ, Zhao R, Zhao ZJ (2001). "Molecular cloning and characterization of SPAP1, an inhibitory receptor.". Biochem. Biophys. Res. Commun. 280 (3): 768-75. doi:10.1006/bbrc.2000.4213. PMID 11162587.
Davis RS, Wang YH, Kubagawa H, Cooper MD (2001). "Identification of a family of Fc receptor homologs with preferential B cell expression.". Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9772-7. doi:10.1073/pnas.171308498. PMID 11493702.
Miller I, Hatzivassiliou G, Cattoretti G, et al. (2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells.". Blood 99 (8): 2662-9. PMID 11929751.
Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1.". Immunogenetics 54 (2): 87-95. doi:10.1007/s00251-002-0436-x. PMID 12037601.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819-24. doi:10.1110/ps.04682504. PMID 15340161.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL.". Immunogenetics 59 (4): 323-8. doi:10.1007/s00251-007-0195-9. PMID 17273841.