Farnesyl-diphosphate kinase

From Wikipedia, the free encyclopedia

In enzymology, a farnesyl-diphosphate kinase (EC 2.7.4.18) is an enzyme that catalyzes the chemical reaction

ATP + farnesyl diphosphate ADP + farnesyl triphosphate

Thus, the two substrates of this enzyme are ATP and farnesyl diphosphate, whereas its two products are ADP and farnesyl triphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:farnesyl-diphosphate phosphotransferase. This enzyme is also called farnesyl pyrophosphate kinase.

[edit] References

• IUBMB entry for 2.7.4.18
• BRENDA references for 2.7.4.18 (Recommended.)
• PubMed references for 2.7.4.18
• PubMed Central references for 2.7.4.18
• Google Scholar references for 2.7.4.18
• Shechter I (1974). "Phosphate transfer from trans-farnesyl triphosphate to AMP in Gibberella fujikuroi". Biochim. Biophys. Acta. 362: 233–44. PMID 4423368. 

[edit] External links

The CAS registry number for this enzyme class is 50936-43-1.

• IUBMB entry for 2.7.4.18

• KEGG entry for 2.7.4.18

• BRENDA entry for 2.7.4.18

• NiceZyme view of 2.7.4.18

• EC2PDB: PDB structures for 2.7.4.18

• PRIAM entry for 2.7.4.18

• PUMA2 entry for 2.7.4.18

• IntEnz: Integrated Enzyme entry for 2.7.4.18

• MetaCyc entry for 2.7.4.18

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047887: farnesyl diphosphate kinase

• AMIGO entry for GO code 0047887: farnesyl diphosphate kinase