Familial amyloid neuropathy
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| Familial amyloid neuropathy Classification and external resources |
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| ICD-10 | E85.1 |
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| ICD-9 | 277.3 |
| MeSH | D028227 |
The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a rare group of autosomal dominant neuropathies of autonomic and peripheral nerves.
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[edit] Classification
The precursor proteins are: transthyretin (ATTR, the most commonly implicated protein), lysozyme, apolipoprotein B, fibrinogen, apolipoprotein A1, and gelsolin.
Due to the rareness of the other types, it is sometimes associated with transthyretin alone.[1]
[edit] Treatment
Liver transplantation has demonstrated moderate improvement in ATTR familial amyloidosis.[2]
[edit] References
- ^ Delahaye N, Rouzet F, Sarda L, et al (July 2006). "Impact of liver transplantation on cardiac autonomic denervation in familial amyloid polyneuropathy". Medicine (Baltimore) 85 (4): 229–38. doi:. PMID 16862048.
- ^ BU.
[edit] External links
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