FAM3C

From Wikipedia, the free encyclopedia


Family with sequence similarity 3, member C
Identifiers
Symbol(s) FAM3C; GS3786
External IDs OMIM: 608618 MGI: 107892 HomoloGene: 8926
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10447 27999
Ensembl ENSG00000196937 ENSMUSG00000029672
Uniprot Q92520 Q53YY7
Refseq NM_001040020 (mRNA)
NP_001035109 (protein)		 NM_138587 (mRNA)
NP_613053 (protein)
Location Chr 7: 120.78 - 120.82 Mb Chr 6: 22.26 - 22.29 Mb
Pubmed search [1] [2]

Family with sequence similarity 3, member C, also known as FAM3C, is a human gene.[1]

This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. Alternate transcriptional splice variants which encode the same protein have been characterized.[1]

[edit] References

  1. ^ a b Entrez Gene: FAM3C family with sequence similarity 3, member C.

[edit] Further reading

  • "Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097–108. PMID 9847074. 
  • Zhu Y, Xu G, Patel A, et al. (2003). "Cloning, expression, and initial characterization of a novel cytokine-like gene family.". Genomics 80 (2): 144–50. PMID 12160727. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948. 
  • Fortna A, Kim Y, MacLaren E, et al. (2006). "Lineage-specific gene duplication and loss in human and great ape evolution.". PLoS Biol. 2 (7): E207. doi:10.1371/journal.pbio.0020207. PMID 15252450. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Mauri P, Scarpa A, Nascimbeni AC, et al. (2006). "Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers.". FASEB J. 19 (9): 1125–7. doi:10.1096/fj.04-3000fje. PMID 15985535. 
  • Grønborg M, Kristiansen TZ, Iwahori A, et al. (2006). "Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach.". Mol. Cell Proteomics 5 (1): 157–71. doi:10.1074/mcp.M500178-MCP200. PMID 16215274. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Guo J, Cheng H, Zhao S, Yu L (2006). "GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases.". FEBS Lett. 580 (2): 581–4. doi:10.1016/j.febslet.2005.12.076. PMID 16406369. 
  • Waerner T, Alacakaptan M, Tamir I, et al. (2006). "ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells.". Cancer Cell 10 (3): 227–39. doi:10.1016/j.ccr.2006.07.020. PMID 16959614. 
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