FAM3B

From Wikipedia, the free encyclopedia

Family with sequence similarity 3, member B

Identifiers

FAM3B; 2-21; C21orf11; C21orf76; ORF9; PANDER; PRED44

External IDs

OMIM: 608617 MGI: 1270150 HomoloGene: 10766

Gene ontology
Molecular Function:	• cytokine activity
Cellular Component:	• extracellular region • extracellular space • endoplasmic reticulum
Biological Process:	• insulin secretion

Orthologs

Human

Mouse

Refseq

NM_058186 (mRNA)
NP_478066 (protein)

NM_020622 (mRNA)
NP_065647 (protein)

Location

Chr 21: 41.61 - 41.65 Mb

Chr 16: 97.58 - 97.66 Mb

Pubmed search

[1]

[2]

Family with sequence similarity 3, member B, also known as FAM3B, is a human gene.^[1]

[edit] References

^ Entrez Gene: FAM3B family with sequence similarity 3, member B.

[edit] Further reading

Yang J, Robert CE, Burkhardt BR, et al. (2006). "Mechanisms of glucose-induced secretion of pancreatic-derived factor (PANDER or FAM3B) in pancreatic beta-cells.". Diabetes 54 (11): 3217-28. PMID 16249448.
Yang J, Gao Z, Robert CE, et al. (2005). "Structure-function studies of PANDER, an islet specific cytokine inducing cell death of insulin-secreting beta cells.". Biochemistry 44 (34): 11342-52. doi:10.1021/bi0503908. PMID 16114871.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Zhu Y, Xu G, Patel A, et al. (2003). "Cloning, expression, and initial characterization of a novel cytokine-like gene family.". Genomics 80 (2): 144-50. PMID 12160727.
Reymond A, Friedli M, Henrichsen CN, et al. (2002). "From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map.". Genomics 78 (1-2): 46-54. doi:10.1006/geno.2001.6640. PMID 11707072.
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311-9. doi:10.1038/35012518. PMID 10830953.