Image:Evh.png

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[edit] Summary

The Domain Organisation of EVH proteins (from amino terminus (left) to carboxy terminus (right)). 1) EVH1 domain - responsible for correct localisation EVH proteins - binds FP4 motifs. 2) PxxP motifs - bind SH2 domains] of SRC and ABL kinases - possibly responsible for regulation. 3) GP5 motifs - Bind the actin carrier protein Profilin 4) G-Actin binding site - Binds G-(monomeric)actin. 5) F-actin binding site - Binds F-(polymerised) actin. 6) Tetramerisation helix - allows EVH proteins to tetramerise - can be homo- & hetero- tetramers.

[edit] Licensing

I, the creator of this work, hereby grant the permission to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. Subject to disclaimers.

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	Date/Time	Dimensions	User	Comment
current	16:31, 29 January 2007	691×187 (29 KB)	Bassophile (Talk \| contribs)	(The Domain Organisation of EVH proteins (from amino terminus (left) to carboxy terminus (right)). 1) EVH1 domain - responsible for correct localisation EVH proteins - binds FP4 motifs. 2) PxxP motifs - bind SH2 domains] of SRC and ABL [[kinase)