Evans blue
From Wikipedia, the free encyclopedia
- For the band, see Evans Blue
| Evans blue | |
|---|---|
 |
|
| Identifiers | |
| CAS number | [314-13-6] |
| PubChem | |
| MeSH | |
| Properties | |
| Molecular formula | C34H24N6Na4O14S4 |
| Molar mass | 960.809 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
T-1824 or Evans Blue, also rendered as Evan's Blue, is an Azo Compound dye which has a very high affinity for serum albumin.
Because of this, it can be useful in physiology in estimating the proportion of body water contained in blood plasma.[1]
Evans blue is also used to assess the permeability of the blood-brain barrier to macromolecules. Because serum albumin cannot cross the barrier, normally the neural tissue remains unstained.[2]
It was named after Herbert McLean Evans, an American chemist.
[edit] See also
[edit] References
- ^ Physiology at MCG 7/7ch02/7ch02p17
- ^ Hawkins BT, Egleton RD (2006). "Fluorescence imaging of blood-brain barrier disruption". Journal of Neuroscience Methods 151 (2): 262–7. doi:.
[edit] External links
- el-Sayed H, Goodall S, Hainsworth R (1995). "Re-evaluation of Evans blue dye dilution method of plasma volume measurement". Clin Lab Haematol 17 (2): 189–94. PMID 8536425.
 |
This chemistry article is a stub. You can help Wikipedia by expanding it. |
