Eukaryotic elongation factors

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Eukaryotic elongation factors are very similar to those in prokaryotes.

Elongation in eukaryotes is carried out with two elongation factors:

• eEF-1, whose α and βγ subunits act as counterparts to EF-Tu and EF-Ts, respectively
• eEF-2, the counterpart to prokaryotic EF-G

[edit] Genes

• EEF1A1, EEF1A2, EEF1A3
• EEF1B1, EEF1B2, EEF1B3, EEF1B4
• EEF1D, EEF1E1, EEF1G
• EEF2

[edit] External links

• MeSH Peptide+Elongation+Factor+1
• MeSH Peptide+Elongation+Factor+2
• nobelprize.org Explaining the function of eukaryotic elongation factors

v • d • e Protein biosynthesis: translation (prokaryotic, eukaryotic) Ribosomal proteins Initiation factor (Prokaryotic, Eukaryotic) - Elongation factor (Prokaryotic, Eukaryotic) - Release factor (Prokaryotic, Eukaryotic) - Ribosomal protein s6 Other concepts Aminoacyl tRNA synthetase - Reading frame - Start codon - Shine-Dalgarno sequence/Kozak consensus sequence

v • d • e Acid anhydride hydrolases: GTPases/G proteins (EC 3.6.5) 3.6.5.1: Heterotrimeric G protein Gαs - Gαi (GNAI1, GNAI2, GNAI3) - Gαq/11 (GNAQ, GNA11) - Gα12/13 (GNA12, GNA13) - Transducin (GNAT1, GNAT2) 3.6.5.2: Small GTPase > Ras superfamily Ras - Rab (Rab27) - Arf (Arf6) - Ran - Rheb - Rho family (RhoA, RhoB, CDC42, Rac1) - Rap 3.6.5.3: Elongation factor Prokaryotic - Eukaryotic 3.6.5.5-6: Other Dynamin (is a GTPase, is not a G protein) - Tubulin