Etidronic acid

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Etidronic acid
Systematic (IUPAC) name
(1-hydroxy-1-phosphono-ethyl)phosphonic acid
Identifiers
CAS number	2809-21-4
ATC code	M05BA01 M05BB01
PubChem	3305
DrugBank	APRD00964
Chemical data
Formula	C2H8O7P2
Mol. mass	206.028 g/mol
Pharmacokinetic data
Bioavailability	3%
Metabolism	Nil
Half life	1 to 6 hours
Excretion	Renal and fecal
Therapeutic considerations
Licence data	US
Pregnancy cat.	C(US)
Legal status	℞ Prescription only
Routes	Oral, intravenous

Etidronic acid (INN) or etidronate disodium (trade name Didronel) is a bisphosphonate used to strengthen bone, treat osteoporosis, and treat Paget's disease of bone.

[edit] Chelating Agent and Anti-oxidant

Etidronic acid is a chelating agent and may be added to bind or, to some extent, counter the effects of substances, such as arsenic, iron, or other metal ions (that can occur in the presence of some soaps), which may be discharged as a component of grey wastewater and could conceivably contaminate groundwater supplies. Etidronic acid also acts to retard rancidification and oxidation of fatty acids. While etidronic acid has not been limited from inclusion in cosmetics and does have legitimate uses, it is recommended that, as with most cosmetic products (particularly soaps), the product should be thoroughly rinsed from the skin after use.

Etidronic acid is listed as an ingredient of several cosmetic formulations. Several examples of Etidronic acid's presence in soap products are: Propolis soap, Dove body wash, Axe body wash, Lever 2000 body wash, Yardley of London, Johnson and Johnson's Lavender, Chamomile Creamy Baby Soap bar and Tesco Pure Soap bar.

Etidronic acid is also included among swimming pool chemicals. It is used as a stain inhibitor to prevent metal ions coming out of solution and staining the sides of swimming pools.

v • d • e Drugs for treatment of bone diseases (M05) Bisphosphonates Nitrogenous (Pamidronic acid, Alendronic acid, Ibandronic acid, Risedronic acid, Zoledronic acid) - Non-nitrogenous (Etidronic acid, Clodronic acid, Tiludronic acid) Bone morphogenetic proteins Dibotermin alfa - Eptotermin alfa Other Ipriflavone - Aluminium chlorohydrate - Strontium ranelate - Odanacatib