Ethanolaminephosphotransferase

From Wikipedia, the free encyclopedia

In enzymology, an ethanolaminephosphotransferase (EC 2.7.8.1) is an enzyme that catalyzes the chemical reaction

CDP-ethanolamine + 1,2-diacylglycerol CMP + a phosphatidylethanolamine

Thus, the two substrates of this enzyme are CDP-ethanolamine and 1,2-diacylglycerol, whereas its two products are CMP and phosphatidylethanolamine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase. Other names in common use include EPT, diacylglycerol ethanolaminephosphotransferase, CDPethanolamine diglyceride phosphotransferase, and phosphorylethanolamine-glyceride transferase. This enzyme participates in 3 metabolic pathways: aminophosphonate metabolism, glycerophospholipid metabolism, and ether lipid metabolism.

[edit] References

• IUBMB entry for 2.7.8.1
• BRENDA references for 2.7.8.1 (Recommended.)
• PubMed references for 2.7.8.1
• PubMed Central references for 2.7.8.1
• Google Scholar references for 2.7.8.1
• KENNEDY EP, WEISS SB (1956). "The function of cytidine coenzymes in the biosynthesis of phospholipides". J. Biol. Chem. 222: 193–214. PMID 13366993. 

[edit] External links

The CAS registry number for this enzyme class is 9026-19-1.

• IUBMB entry for 2.7.8.1

• KEGG entry for 2.7.8.1

• BRENDA entry for 2.7.8.1

• NiceZyme view of 2.7.8.1

• EC2PDB: PDB structures for 2.7.8.1

• PRIAM entry for 2.7.8.1

• PUMA2 entry for 2.7.8.1

• IntEnz: Integrated Enzyme entry for 2.7.8.1

• MetaCyc entry for 2.7.8.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004307: ethanolaminephosphotransferase

• AMIGO entry for GO code 0004307: ethanolaminephosphotransferase