ERLIN2

From Wikipedia, the free encyclopedia

ER lipid raft associated 2

Identifiers

ERLIN2; C8orf2; Erlin-2; MGC87072; SPFH2

External IDs

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• cellular_component • endoplasmic reticulum • membrane
Biological Process:	• biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001003790 (mRNA)
NP_001003790 (protein)

NM_153592 (mRNA)
NP_705820 (protein)

Location

Chr 8: 37.71 - 37.73 Mb

Chr 8: 28.49 - 28.51 Mb

Pubmed search

[1]

[2]

ER lipid raft associated 2, also known as ERLIN2, is a human gene.^[1]

[edit] References

^ Entrez Gene: ERLIN2 ER lipid raft associated 2.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Ikegawa S, Isomura M, Koshizuka Y, Nakamura Y (1999). "Cloning and characterization of a novel gene (C8orf2), a human representative of a novel gene family with homology to C. elegans C42.C1.9.". Cytogenet. Cell Genet. 85 (3-4): 227-31. PMID 10449903.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287-92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711-8. doi:10.1101/gr.2435604. PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Garcia MJ, Pole JC, Chin SF, et al. (2005). "A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes.". Oncogene 24 (33): 5235-45. doi:10.1038/sj.onc.1208741. PMID 15897872.
Browman DT, Resek ME, Zajchowski LD, Robbins SM (2007). "Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER.". J. Cell. Sci. 119 (Pt 15): 3149-60. doi:10.1242/jcs.03060. PMID 16835267.
Pearce MM, Wang Y, Kelley GG, Wojcikiewicz RJ (2007). "SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells.". J. Biol. Chem. 282 (28): 20104-15. doi:10.1074/jbc.M701862200. PMID 17502376.