EPS8L1

From Wikipedia, the free encyclopedia

EPS8-like 1

PDB rendering based on 2cy4.

Available structures: 2cy4, 2cy5

Identifiers

Symbol(s)

EPS8L1; DRC3; EPS8R1; FLJ20258; MGC23164; MGC4642; PP10566

External IDs

MGI: 1914675 HomoloGene: 15767

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• cellular_component
Biological Process:	• biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_017729 (mRNA)
NP_060199 (protein)

NM_026146 (mRNA)
NP_080422 (protein)

Location

Chr 19: 60.28 - 60.29 Mb

Chr 7: 4.07 - 4.08 Mb

Pubmed search

[1]

[2]

EPS8-like 1, also known as EPS8L1, is a human gene.^[1]

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Several alternatively spliced transcript variants encoding different isoforms exist.^[1]

[edit] References

^ ^a ^b Entrez Gene: EPS8L1 EPS8-like 1.

[edit] Further reading

Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression.". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724-9. doi:10.1073/pnas.0404089101. PMID 15498874.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Offenhäuser N, Borgonovo A, Disanza A, et al. (2004). "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway.". Mol. Biol. Cell 15 (1): 91-8. doi:10.1091/mbc.E03-06-0427. PMID 14565974.
Tocchetti A, Confalonieri S, Scita G, et al. (2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure.". Genomics 81 (2): 234-44. PMID 12620401.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Wu K, Xu Z, Wang M, et al. (1999). "[Cloning and expression analyses of down-regulated cDNA C6-2A in human esophageal cancer]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi 16 (5): 325-7. PMID 10514543.