Epimerase and racemase

From Wikipedia, the free encyclopedia

Epimerases and racemases are isomerase enzymes that catalyze the inversion of stereochemistry in biological molecules.^[1] Racemases catalyze the stereochemical inversion around the asymmetric carbon atom in a substrate having only one center of asymmetry. Epimerases catalyze the stereochemical inversion of the configuration about an asymmetric carbon atom in a substrate having more than one center of asymmetry; thus interconverting epimers.

[edit] References

1. ^ Tanner, ME. (2002). "Understanding nature's strategies for enzyme-catalyzed racemization and epimerization". Acc. Chem. Res. 35 (4): 237–246. doi:10.1021/ar000056y. PMID 11955052. 

[edit] External links

• http://medical-dictionary.thefreedictionary.com/racemase
• http://medical-dictionary.thefreedictionary.com/epimerase
• MeSH Entry+Term+Epimerases

v • d • e Isomerases: Epimerase and racemases (EC 5.1) Amino-acid racemase Phenylalanine racemase (ATP-hydrolysing) - Serine racemase Other Mandelate racemase - UDP galactose epimerase - Methylmalonyl CoA epimerase