EPC1

From Wikipedia, the free encyclopedia

Enhancer of polycomb homolog 1 (Drosophila)

Identifiers

EPC1; DKFZp781P2312; Epl1

External IDs

Gene ontology
Molecular Function:	• transcription activator activity • transcription repressor activity
Cellular Component:	• nucleus
Biological Process:	• regulation of cell growth • transcription • regulation of transcription, DNA-dependent • chromatin modification

Orthologs

Human

Mouse

Refseq

NM_025209 (mRNA)
NP_079485 (protein)

NM_007935 (mRNA)
NP_031961 (protein)

Location

Chr 10: 32.6 - 32.71 Mb

Chr 18: 6.44 - 6.49 Mb

Pubmed search

[1]

[2]

Enhancer of polycomb homolog 1 (Drosophila), also known as EPC1, is a human gene.^[1]

[edit] References

^ Entrez Gene: EPC1 enhancer of polycomb homolog 1 (Drosophila).

[edit] Further reading

Doyon Y, Côté J (2004). "The highly conserved and multifunctional NuA4 HAT complex.". Curr. Opin. Genet. Dev. 14 (2): 147-54. doi:10.1016/j.gde.2004.02.009. PMID 15196461.
Liedtke W, Meyer G, Faustmann PM, et al. (1997). "Clonal expansion and decreased occurrence of peripheral blood gamma delta T cells of the V delta 2J delta 3 lineage in multiple sclerosis patients.". Int. Immunol. 9 (7): 1031-41. PMID 9237112.
Wang X, Stollar BD (1999). "Immunoglobulin VH gene expression in human aging.". Clin. Immunol. 93 (2): 132-42. doi:10.1006/clim.1999.4781. PMID 10527689.
Shimono Y, Murakami H, Hasegawa Y, Takahashi M (2001). "RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions.". J. Biol. Chem. 275 (50): 39411-9. doi:10.1074/jbc.M006585200. PMID 10976108.
Kenny TP, Semrad TJ, Malyj W, Robbins DL (2001). "Mutational analysis of immunoglobulin germline derived Vlambda4B light chains in rheumatoid arthritis.". Clin. Immunol. 99 (2): 283-90. doi:10.1006/clim.2001.5020. PMID 11318600.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Cai Y, Jin J, Tomomori-Sato C, et al. (2003). "Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.". J. Biol. Chem. 278 (44): 42733-6. doi:10.1074/jbc.C300389200. PMID 12963728.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Doyon Y, Selleck W, Lane WS, et al. (2004). "Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.". Mol. Cell. Biol. 24 (5): 1884-96. PMID 14966270.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Attwooll C, Oddi S, Cartwright P, et al. (2005). "A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner.". J. Biol. Chem. 280 (2): 1199-208. doi:10.1074/jbc.M412509200. PMID 15536069.
Cai Y, Jin J, Florens L, et al. (2005). "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.". J. Biol. Chem. 280 (14): 13665-70. doi:10.1074/jbc.M500001200. PMID 15647280.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285-92. doi:10.1038/nbt1240. PMID 16964243.
Kee HJ, Kim JR, Nam KI, et al. (2007). "Enhancer of polycomb1, a novel homeodomain only protein-binding partner, induces skeletal muscle differentiation.". J. Biol. Chem. 282 (10): 7700-9. doi:10.1074/jbc.M611198200. PMID 17192267.