Epalrestat
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| Epalrestat | |
|---|---|
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| IUPAC name | 2-[(5Z)-5-[(E)-3-cyclohexyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid |
| Identifiers | |
| CAS number | [82159-09-9] |
| PubChem | |
| SMILES | CC(=CC1=CC=CC=C1)C= C2C(=O)N(C(=S)S2)CC(=O)O |
| Properties | |
| Molecular formula | C15H13NO3S2 |
| Molar mass | 319.401 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Epalrestat is an aldose reductase inhibitor.
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Long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, particularly in subjects with good glycemic control and limited microangiopathy.
