Enterococcus faecalis

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Enterococcus faecalis
Enterococcus faecalis as viewed through a scanning electron microscope
Enterococcus faecalis as viewed through a scanning electron microscope
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Enterococcaceae
Genus: Enterococcus
Species: E. faecalis
Binomial name
Enterococcus faecalis
(Orla-Jensen 1919)
Schleifer & Kilpper-Bälz 1984

Enterococcus faecalis also known as Group D Streptococcus (cocci) is a Gram-positive commensal bacterium inhabiting the gastrointestinal tracts of humans and other mammals.[1] Like other species in the genus Enterococcus, E. faecalis can cause life-threatening infections in humans and monkeys, especially in the nosocomial (hospital) environment: the naturally high levels of antibiotic resistance found in E. faecalis contribute to its pathogenicity.[1] E. faecalis presents as a non-motile microorganism that is facultatively anaerobic, it ferments glucose without gas production, and does not produce a catalase reaction with hydrogen peroxide. E. faecalis displays gamma hemolysis (γ-hemolysis). It produces a reduction of litmus milk, but does not liquefy gelatin. Growth of nutrient broth is consistent with being facultatively anaerobic.

[edit] Pathogenesis

E. faecalis can cause endocarditis, as well as bladder, prostate, and epididymal infections; nervous system infections are less common.[1][2]

E. faecalis is resistant to many commonly used antimicrobial agents (aminoglycosides, aztreonam, cephalosporins, clindamycin, the semi-synthetic penicillins nafcillin and oxacillin, and trimethoprim-sulfamethoxazole). Exposure to cephalosporins is a particularly important risk factor for colonization and infection with enterococci.

[edit] Historical

Prior to 1984, enterococci were members of the genus Streptococcus: thus E. faecalis was known as Streptococcus faecalis.[3]

[edit] References

  1. ^ a b c Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology, 4th ed., McGraw Hill, 294–5. ISBN 0-8385-8529-9. 
  2. ^ Pelletier LL (1996). Microbiology of the Circulatory System. in: Baron's Medical Microbiology (Baron S et al, eds.), 4th ed., Univ of Texas Medical Branch. ISBN 0-9631172-1-1. 
  3. ^ Schleifer KH; Kilpper-Balz R (1984). "Transfer of Streptococcus faecalis and Streptococcus faecium to the genus Enterococcus nom. rev. as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov.". Int. J. Sys. Bacteriol. 34: 31–34.