Talk:Endoplasmic reticulum
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i think SER and RER are so incredibly different they really should have different pages --sovbeos
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[edit] Include ERAD?
One should also include ERAD, the Endoplasmic Reticulum Associated Protein Degradation, and link to the short article explaining it. Since English is not my native language, it would be nice of someone could write a few sentences about it in this artice.
[edit] B-class
It seems the page has improved and I think can now be considered B class. What say you? - IlyaV
i for one think this is a very good website. children might not understand but adults and teen agers will find this a great place to learn about the E.R!!!-BS47
I've changed it to B since no one disagreed... IlyaV 01:20, 21 February 2007 (UTC)
[edit] Research website
Research website: Spurger llspurge@utmb.edu for Cell Biology Graduate Program Copyright © 2002 The University of Texas Medical Branch. Please review our privacy policy and Internet guidelines.
Endoplasmic reticulum is a network of tubules, vesicles and sacs that are interconnected. They may serve specialized functions in the cell including protein synthesis, sequestration of calcium, production of steroids, storage and production of glycogen, and insertion of membrane proteins. The endoplasmic reticulum or ER (endoplasmic means "within the cytoplasm," reticulum means "little net") is an organelle found in all eukaryotic cells. It is part of the endomembrane system. The ER modifies proteins, makes macromolecules, and transfers substances throughout the cell. Prokaryotic organisms do not have membranous organelles and thus do not have an ER. The basic structure and composition of the ER is similar to the plasma membrane, although it is actually an extension of the nuclear membrane. The ER is the site of the translation, folding, and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and other integral membrane proteins) as well as proteins that are to be secreted or "exocytosed" from the cell (e.g., digestive enzymes). Structure…Figure 1 : Image of nucleus, endoplasmic reticulum and Golgi apparatus (1) Nucleus. (2) Nuclear pore. (3) Rough endoplasmic reticulum (rER). (4) Smooth endoplasmic reticulum (sER). (5) Ribosome on the rough ER. (6) Proteins that are transported. (7) Transport vesicle. (8) Golgi apparatus. (9) Cis face of the Golgi apparatus. (10) Trans face of the Golgi apparatus. (11) Cisternae of the Golgi apparatus.The ER consists of an extensive membrane network of tubes and cisternae (sac-like structures) held together by the cytoskeleton. The membrane encloses a space, the cisternal space (or internal lumen) from the cytosol. This space is acting as a gateway. Parts of the ER membrane are continuous with the outer membrane of the nuclear envelope, and the cisternal space of the ER is continuous with the space between the two layers of the nuclear envelope (the intermembrane space). Parts of the ER are covered with ribosomes (which assemble amino acids into proteins based on instructions from the nucleus). Their rough appearance under electron microscopy led to their being called rough ER (rER), other parts are free of ribosomes and are called smooth ER (sER). The ribosomes on the surface of the rough ER insert the freshly produced proteins directly into the ER, which processes them and then passes them on to the Golgi apparatus (Fig. 1). The rough and smooth ER differ in both appearance and function but are contiguous with each other.
Magnus, did you make that image yourself? That is incredible. --LMS
- Yup, from my "Nupedia evacuation". There are more like this :) --Magnus Manske
[edit] Image problem
Suddenly your images are no longer in the page. (In the ribosome article this changed in the last couple of hours.) When I click on the hyperlink the image appears in its own page. Then I have to click the back and forward arrows to compare the image to the caption. Inconvenient. (Even if I could set my browser to display the image in its own window, or if you could program it into a pop up window, there will always be cases where, due to the size of the image and the location of the caption in page, I would have to click on the windows to compare the image to its caption.'
In this case, the text does not flow properly around the hyperlink to the image, unless I maximize the window. I see the text and the caption printed on top of each other.
The Solo Owl 03:43 Nov 4, 2002 (UTC)
- I think it's just a temporary glitch while the rules about what images can and cannot be shown are changed - somebody will sort it out in time. By the way, four or more hyphens, thus: ---- will make a horizonal rule, and a colon at the start of a line will indent it. --Camembert
Thanks for the tip, I'm new here. I'll try it now.
Manske, thank you so much for the articles and illustrations. Made for a very entertaining and educational weekend. Let us know when your textbooks come out! The Solo Owl 04:23 Nov 4, 2002 (UTC)
I was surprised to see the expletives in sentence 2. It is not too clear what is meant by them, either. The Solo Owl 06:33 Nov 4, 2002 (UTC)
[edit] Unused Image
The image at Image:Nucleus_ER.png (below) isn't currently used in this article (or elsewhere), it would be good to use, if somebody could identify all the numbers for the caption. --Lexor|Talk 05:38, 3 Mar 2004 (UTC)
[edit] sorry
sorry for deleting the info!
i didnt mean to!
[edit] Identification of the numbers from the image
Hello everybody!
These are the identifications needed:
- (1) Nucleus
- (2) Ribosomes
- (3) Pores (of the nucleus)
- (4) Nucleolus
- (5) Chromatin
- (6) Nucleo membrane
- (7) Endoplasmic reticulum
- (8) Nucleoplasma
NOTE: Because for numbers 5 and 8 it is not shown clearly (on the image) what are they pointing at, it can be vice-versa for the explanation.
Regards.
- Those identifications aren't completely correct.
- (1) Nuclear membrane
- (2) Ribosomes
- (3) Nuclear pore
- (4) Nucleolus
- (5) Chromatin
- (6) Cell membrane
- (7) Rough endoplasmic reticulum
- (8) Nucleoplasma
To be honest its quite an unclear, poor drawing and not really worth adding anyway. 80.42.107.101 13:37, 12 April 2006 (UTC)
[edit] Graffiti.
Can someone fix the graffiti at the bottom? It isn't showing up on the edit page for me.
[edit] plural
Shouldn't words like reticulum that have irregular plurals have their plurals indicated. I would have doen it, but with the 'ER' stuff, I didn't know where it would best be placed. Kdammers 08:29, 8 May 2006 (UTC)
[edit] Sprotected
I've decided to try sprotecting this for a while. It's been vandalised many times per day since the beginning of September, mostly with (individually trivial) additions of hoax info or graffiti. I really can't figure out why it's getting such attention - articles covered in school classes get a degree of the usual "Kevin is Kewl" type vandalism, but rarely this much. Blocking the anons is useless (it's rarely the same one twice) and we've not been succesful in detecting and removing all the vandalism (I just removed a couple of pieces that have been there for days, unnoticed). I'm guessing that maybe some website or noticeboard somewhere has a "wouldn't it be cool to put junk into the Wikipedia ER article"; on that theory I think we should sprotect it for a couple of weeks and see if the nonsense dies down. -- Finlay McWalter | Talk 14:49, 8 October 2006 (UTC)
- 11 days later and no vandalism at all (but very few other edits too). I've unprotected - let's see how we get on. -- Finlay McWalter | Talk 21:43, 19 October 2006 (UTC)
[edit] SER Functions
I'm not exactly sure about all of this but according to my teacher, the SER also detoxifies drugs and breaks down glycogen into glucose(in liver cells). If the info is there, I'm just not seeing it but I don't even know if its correct. Also, why do you list many of the SER's functions under the structure heading? Arizonabass 20:42, 15 January 2007 (UTC)
[edit] SR
I have checked quite a few secondary literatures, and am pretty sure that the SR is not only found in STRIATED MUSCLES but also SMOOTH MUSCLES. Please revise this bit of info in the article, LOL. Cheers128.250.6.246
- Does "SR" refer to smooth endoplasmic reticulum or sarcoplasmic reticulum? What exactly is the discrepancy in the article? --David Iberri (talk) 06:30, 13 April 2007 (UTC)
SER and RER are in all cells, it's just an issue of how much and is it actually visible.
[edit] Layperson request for info
I read on some page in wikipedia this: "The endoplasmic reticulum is a synthesis and transport organelle that is an extension of the nuclear envelope." This refers to the ER's relationship to the nuclear envelope, and in general the nucleus. Could this relationship be put somewhere in the actual ER article, if this is factual? Thanks, Rhetth (talk) 20:57, 20 March 2008 (UTC)
