EML4

From Wikipedia, the free encyclopedia

Echinoderm microtubule associated protein like 4

Identifiers

EML4; C2orf2; DKFZp686P18118; ELP120; FLJ10942; FLJ32318; ROPP120

External IDs

OMIM: 607442 MGI: 1926048 HomoloGene: 56841

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• cytoplasm • microtubule
Biological Process:	• microtubule-based process • mitosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_019063 (mRNA)
NP_061936 (protein)

NM_199466 (mRNA)
NP_955760 (protein)

Location

Chr 2: 42.25 - 42.41 Mb

Chr 17: 83.31 - 83.39 Mb

Pubmed search

[1]

[2]

Echinoderm microtubule associated protein like 4, also known as EML4, is a human gene.^[1]

[edit] References

^ Entrez Gene: EML4 echinoderm microtubule associated protein like 4.

[edit] Further reading

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.
Heidebrecht HJ, Buck F, Pollmann M, et al. (2000). "Cloning and localization of C2orf2(ropp120), a previously unknown WD repeat protein.". Genomics 68 (3): 348–50. doi:10.1006/geno.2000.6301. PMID 10995578.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
Pollmann M, Parwaresch R, Adam-Klages S, et al. (2006). "Human EML4, a novel member of the EMAP family, is essential for microtubule formation.". Exp. Cell Res. 312 (17): 3241–51. doi:10.1016/j.yexcr.2006.06.035. PMID 16890222.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.