ELP3

From Wikipedia, the free encyclopedia

Elongation protein 3 homolog (S. cerevisiae)

Identifiers

ELP3; FLJ10422

External IDs

MGI: 1921445 HomoloGene: 7105

Gene ontology
Molecular Function:	• catalytic activity • iron ion binding • N-acetyltransferase activity • transferase activity • metal ion binding • hydrogen ion transporting ATP synthase activity, rotational mechanism • hydrogen ion transporting ATPase activity, rotational mechanism • iron-sulfur cluster binding
Cellular Component:	• cytoplasm • proton-transporting two-sector ATPase complex
Biological Process:	• ATP synthesis coupled proton transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018091 (mRNA)
NP_060561 (protein)

NM_028811 (mRNA)
NP_083087 (protein)

Location

Chr 8: 28.01 - 28.1 Mb

Chr 14: 64.48 - 64.55 Mb

Pubmed search

[1]

[2]

Elongation protein 3 homolog (S. cerevisiae), also known as ELP3, is a human gene.^[1]

[edit] References

^ Entrez Gene: ELP3 elongation protein 3 homolog (S. cerevisiae).

[edit] Further reading

Rengo F, Brevetti G, Piscione F, et al. (1977). "[Behavior of some metabolic parameters during post-ischemic and post-contraction vasodilation in normal subjects]". Bollettino della Società italiana di cardiologia 20 (12): 1801–6. PMID 10936.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Ninomiya Y, Okada M, Kotomura N, et al. (1996). "Genomic organization and isoforms of the mouse ELP gene.". J. Biochem. 118 (2): 380–9. PMID 8543574.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Hawkes NA, Otero G, Winkler GS, et al. (2002). "Purification and characterization of the human elongator complex.". J. Biol. Chem. 277 (4): 3047–52. doi:10.1074/jbc.M110445200. PMID 11714725.
Kim JH, Lane WS, Reinberg D (2002). "Human Elongator facilitates RNA polymerase II transcription through chromatin.". Proc. Natl. Acad. Sci. U.S.A. 99 (3): 1241–6. doi:10.1073/pnas.251672198. PMID 11818576.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
Kouskouti A, Talianidis I (2005). "Histone modifications defining active genes persist after transcriptional and mitotic inactivation.". EMBO J. 24 (2): 347–57. doi:10.1038/sj.emboj.7600516. PMID 15616580.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.
Han Q, Hou X, Su D, et al. (2007). "hELP3 subunit of the Elongator complex regulates the transcription of HSP70 gene in human cells.". Acta Biochim. Biophys. Sin. (Shanghai) 39 (6): 453–61. PMID 17558451.