EIF3J

From Wikipedia, the free encyclopedia

Eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa

Identifiers

EIF3S1; eIF3-alpha; eIF3-p35; eIF3j

External IDs

OMIM: 603910 MGI: 1925905 HomoloGene: 37845

Gene ontology
Molecular Function:	• translation initiation factor activity • protein binding
Cellular Component:	• eukaryotic translation initiation factor 3 complex
Biological Process:	• translation • regulation of translational initiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003758 (mRNA)
NP_003749 (protein)

NM_144545 (mRNA)
NP_653128 (protein)

Location

Chr 15: 42.62 - 42.64 Mb

Chr 2: 121.74 - 121.74 Mb

Pubmed search

[1]

[2]

Eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa, also known as EIF3S1, is a human gene.^[1]

[edit] References

^ Entrez Gene: EIF3S1 eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa.

[edit] Further reading

Asano K, Kinzy TG, Merrick WC, Hershey JW (1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3.". J. Biol. Chem. 272 (2): 1101–9. PMID 8995409.
Méthot N, Rom E, Olsen H, Sonenberg N (1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170.". J. Biol. Chem. 272 (2): 1110–6. PMID 8995410.
Block KL, Vornlocher HP, Hershey JW (1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3.". J. Biol. Chem. 273 (48): 31901–8. PMID 9822659.
Bushell M, Wood W, Clemens MJ, Morley SJ (2000). "Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis.". Eur. J. Biochem. 267 (4): 1083–91. PMID 10672017.
Valásek L, Hasek J, Nielsen KH, Hinnebusch AG (2001). "Dual function of eIF3j/Hcr1p in processing 20 S pre-rRNA and translation initiation.". J. Biol. Chem. 276 (46): 43351–60. doi:10.1074/jbc.M106887200. PMID 11560931.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Mayeur GL, Fraser CS, Peiretti F, et al. (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.". Eur. J. Biochem. 270 (20): 4133–9. PMID 14519125.
Fraser CS, Lee JY, Mayeur GL, et al. (2004). "The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.". J. Biol. Chem. 279 (10): 8946–56. doi:10.1074/jbc.M312745200. PMID 14688252.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
ElAntak L, Tzakos AG, Locker N, Lukavsky PJ (2007). "Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit.". J. Biol. Chem. 282 (11): 8165–74. doi:10.1074/jbc.M610860200. PMID 17190833.