EIF3H

From Wikipedia, the free encyclopedia

Eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa

Identifiers

EIF3S3; MGC102958; eIF3-gamma; eIF3-p40; eIF3h

External IDs

OMIM: 603912 MGI: 1915385 HomoloGene: 2785

Gene ontology
Molecular Function:	• translation initiation factor activity • protein binding
Cellular Component:	• eukaryotic translation initiation factor 3 complex
Biological Process:	• translation • regulation of translational initiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003756 (mRNA)
NP_003747 (protein)

NM_080635 (mRNA)
NP_542366 (protein)

Location

Chr 8: 117.73 - 117.85 Mb

Chr 15: 51.62 - 51.7 Mb

Pubmed search

[1]

[2]

Eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa, also known as EIF3S3, is a human gene.^[1]

[edit] References

^ Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Asano K, Kinzy TG, Merrick WC, Hershey JW (1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3.". J. Biol. Chem. 272 (2): 1101-9. PMID 8995409.
Méthot N, Rom E, Olsen H, Sonenberg N (1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170.". J. Biol. Chem. 272 (2): 1110-6. PMID 8995410.
Asano K, Vornlocher HP, Richter-Cook NJ, et al. (1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly.". J. Biol. Chem. 272 (43): 27042-52. PMID 9341143.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Block KL, Vornlocher HP, Hershey JW (1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3.". J. Biol. Chem. 273 (48): 31901-8. PMID 9822659.
Saramäki O, Willi N, Bratt O, et al. (2001). "Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer.". Am. J. Pathol. 159 (6): 2089-94. PMID 11733359.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Morris JA, Kandpal G, Ma L, Austin CP (2004). "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.". Hum. Mol. Genet. 12 (13): 1591-608. PMID 12812986.
Mayeur GL, Fraser CS, Peiretti F, et al. (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.". Eur. J. Biochem. 270 (20): 4133-9. PMID 14519125.
Okamoto H, Yasui K, Zhao C, et al. (2003). "PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas.". Hepatology 38 (5): 1242-9. doi:10.1053/jhep.2003.50457. PMID 14578863.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Savinainen KJ, Linja MJ, Saramäki OR, et al. (2004). "Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer.". Br. J. Cancer 90 (5): 1041-6. doi:10.1038/sj.bjc.6601648. PMID 14997205.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
Savinainen KJ, Helenius MA, Lehtonen HJ, Visakorpi T (2006). "Overexpression of EIF3S3 promotes cancer cell growth.". Prostate 66 (11): 1144-50. doi:10.1002/pros.20452. PMID 16652384.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.