EIF3C

From Wikipedia, the free encyclopedia

Eukaryotic translation initiation factor 3, subunit 8, 110kDa

Identifiers

EIF3S8; eIF3-p110; eIF3c

External IDs

OMIM: 603916 MGI: 1926966 HomoloGene: 2781

Gene ontology
Molecular Function:	• translation initiation factor activity
Cellular Component:	• eukaryotic translation initiation factor 3 complex
Biological Process:	• translational initiation • regulation of translational initiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_001037808 (mRNA)
NP_001032897 (protein)

XM_993422 (mRNA)
XP_998516 (protein)

Location

Chr 16: 28.63 - 28.65 Mb

n/a

Pubmed search

[1]

[2]

Eukaryotic translation initiation factor 3, subunit 8, 110kDa, also known as EIF3S8, is a human gene.^[1]

[edit] References

^ Entrez Gene: EIF3S8 eukaryotic translation initiation factor 3, subunit 8, 110kDa.

[edit] Further reading

Asano K, Kinzy TG, Merrick WC, Hershey JW (1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3.". J. Biol. Chem. 272 (2): 1101-9. PMID 8995409.
Méthot N, Rom E, Olsen H, Sonenberg N (1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170.". J. Biol. Chem. 272 (2): 1110-6. PMID 8995410.
Block KL, Vornlocher HP, Hershey JW (1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3.". J. Biol. Chem. 273 (48): 31901-8. PMID 9822659.
Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.". Genomics 60 (3): 295-308. doi:10.1006/geno.1999.5927. PMID 10493829.
Morris-Desbois C, Bochard V, Reynaud C, Jalinot P (1999). "Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.". J. Cell. Sci. 112 ( Pt 19): 3331-42. PMID 10504338.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Olsen DS, Savner EM, Mathew A, et al. (2003). "Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo.". EMBO J. 22 (2): 193-204. doi:10.1093/emboj/cdg030. PMID 12514125.
Mayeur GL, Fraser CS, Peiretti F, et al. (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.". Eur. J. Biochem. 270 (20): 4133-9. PMID 14519125.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707-16. doi:10.1038/nbt971. PMID 15146197.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells.". J. Proteome Res. 4 (4): 1339-46. doi:10.1021/pr050048h. PMID 16083285.
Gevaert K, Staes A, Van Damme J, et al. (2006). "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.". Proteomics 5 (14): 3589-99. doi:10.1002/pmic.200401217. PMID 16097034.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome 16 (12): 942-54. doi:10.1007/s00335-005-0075-2. PMID 16341674.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285-92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.