Ectoine synthase

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In enzymology, an ectoine synthase (EC 4.2.1.108) is an enzyme that catalyzes the chemical reaction

N₄-acetyl-L-2,4-diaminobutanoate $\rightleftharpoons$ L-ectoine + H₂O

Hence, this enzyme has one substrate, N4-acetyl-L-2,4-diaminobutanoate, and two products, L-ectoine and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming). Other names in common use include N-acetyldiaminobutyrate dehydratase, N-acetyldiaminobutanoate dehydratase, L-ectoine synthase, EctC, and 4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming). This enzyme participates in glycine, serine and threonine metabolism.

[edit] References

IUBMB entry for 4.2.1.108
BRENDA references for 4.2.1.108 (Recommended.)
PubMed references for 4.2.1.108
PubMed Central references for 4.2.1.108
Google Scholar references for 4.2.1.108
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Louis P, Galinski EA (Pt 4). "Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli". Microbiology. 143: 1141–9. PMID 9141677.