Echinocandin

From Wikipedia, the free encyclopedia

Echinocandins are antifungal drugs that inhibit the synthesis of glucan in the cell wall, probably via the enzyme 1,3-β glucan synthase. They are fungicidal against yeast and fungistatic against mold.

• Anidulafungin
• Caspofungin
• Micafungin

[edit] References

• Wagner C, Graninger W, Presterl E, Joukhadar C (2006). "The echinocandins: comparison of their pharmacokinetics, pharmacodynamics and clinical applications". Pharmacology 78 (4): 161–77. doi:10.1159/000096348. PMID 17047411. 
• Morris M, Villmann M (2006). "Echinocandins in the management of invasive fungal infections, part 1". Am J Health Syst Pharm 63 (18): 1693–703. doi:10.2146/ajhp050464.p1. PMID 16960253. 
• Morris M, Villmann M (2006). "Echinocandins in the management of invasive fungal infections, Part 2". Am J Health Syst Pharm 63 (19): 1813–20. doi:10.2146/ajhp050464.p2. PMID 16990627. 

v • d • e Antifungals (D01 and J02) Antibiotics Griseofulvin • polyene antimycotics (Natamycin, Nystatin) Topical azoles imidazoles (Bifonazole, Clomidazole, Clotrimazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole, Neticonazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole) • triazoles (Fluconazole) • benzimidazole (Thiabendazole) Other topicals Ciclopirox • Ethylparaben • Flucytosine • Salicylic acid • Selenium sulfide • Tolnaftate • Undecylenic acid • allylamines (Amorolfine, Butenafine, Naftifine, Terbinafine) For systemic use Griseofulvin • allylamine (Terbinafine) • polyene antimycotic (Amphotericin B) • triazoles (Itraconazole, Posaconazole, Voriconazole) • echinocandins (Anidulafungin, Caspofungin, Micafungin) Other Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle