DUSP19

From Wikipedia, the free encyclopedia

Dual specificity phosphatase 19

Identifiers

DUSP19; DUSP17; MGC138210; SKRP1; TS-DSP1

External IDs

MGI: 1915332 HomoloGene: 41565

Gene ontology
Molecular Function:	• protein tyrosine phosphatase activity • protein binding • protein tyrosine/threonine phosphatase activity • JUN kinase phosphatase activity • hydrolase activity
Cellular Component:	• cytoplasm
Biological Process:	• inactivation of MAPK activity • protein amino acid dephosphorylation • JNK cascade

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_080876 (mRNA)
NP_543152 (protein)

NM_024438 (mRNA)
NP_077758 (protein)

Location

Chr 2: 183.65 - 183.67 Mb

Chr 2: 80.42 - 80.43 Mb

Pubmed search

[1]

[2]

Dual specificity phosphatase 19, also known as DUSP19, is a human gene.^[1]

[edit] References

^ Entrez Gene: DUSP19 dual specificity phosphatase 19.

[edit] Further reading

Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724-31. doi:10.1038/nature03466. PMID 15815621.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Cheng H, Gao Q, Jiang M, et al. (2003). "Molecular cloning and characterization of a novel human protein phosphatase, LMW-DSP3.". Int. J. Biochem. Cell Biol. 35 (2): 226-34. PMID 12479873.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Zama T, Aoki R, Kamimoto T, et al. (2002). "Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway.". J. Biol. Chem. 277 (26): 23919-26. doi:10.1074/jbc.M200838200. PMID 11959862.
Zama T, Aoki R, Kamimoto T, et al. (2002). "A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway.". J. Biol. Chem. 277 (26): 23909-18. doi:10.1074/jbc.M200837200. PMID 11959861.