DTYMK

From Wikipedia, the free encyclopedia


Deoxythymidylate kinase (thymidylate kinase)
PDB rendering based on 1e2d.
Available structures: 1e2d, 1e2e, 1e2f, 1e2g, 1e2q, 1e98, 1e99, 1e9a, 1e9b, 1e9c, 1e9d, 1e9e, 1e9f, 1nmx, 1nmy, 1nmz, 1nn0, 1nn1, 1nn3, 1nn5
Identifiers
Symbol(s) DTYMK; CDC8; TMPK; TYMK
External IDs OMIM: 188345 MGI: 108396 HomoloGene: 6285
Orthologs
Human Mouse
Entrez 1841 21915
Ensembl n/a ENSMUSG00000026281
Refseq NM_012145 (mRNA)
NP_036277 (protein)		 NM_023136 (mRNA)
NP_075625 (protein)
Location n/a Chr 1: 95.62 - 95.63 Mb
Pubmed search [1] [2]

Deoxythymidylate kinase (thymidylate kinase), also known as DTYMK, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: DTYMK deoxythymidylate kinase (thymidylate kinase).

[edit] Further reading

  • Van Rompay AR, Johansson M, Karlsson A (2000). "Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases.". Pharmacol. Ther. 87 (2-3): 189-98. PMID 11008000. 
  • Su JY, Sclafani RA (1991). "Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast.". Nucleic Acids Res. 19 (4): 823-7. PMID 2017365. 
  • Tamiya N, Yusa T, Yamaguchi Y, et al. (1989). "Co-purification of thymidylate kinase and cytosolic thymidine kinase from human term placenta by affinity chromatography.". Biochim. Biophys. Acta 995 (1): 28-35. PMID 2538159. 
  • Cummins RR, Balinsky D (1980). "Activities of some enzymes of pyrimidine and DNA synthesis in a rat transplantable hepatoma and human primary hepatomas, in cell lines derived from these tissues, and in human fetal liver.". Cancer Res. 40 (4): 1235-9. PMID 6244089. 
  • Huang SH, Tang A, Drisco B, et al. (1994). "Human dTMP kinase: gene expression and enzymatic activity coinciding with cell cycle progression and cell growth.". DNA Cell Biol. 13 (5): 461-71. PMID 8024690. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ostermann N, Segura-Peña D, Meier C, et al. (2003). "Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds.". Biochemistry 42 (9): 2568-77. doi:10.1021/bi027302t. PMID 12614151. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
 This protein-related article is a stub. You can help Wikipedia by expanding it.