DRG1

From Wikipedia, the free encyclopedia

Developmentally regulated GTP binding protein 1

Identifiers

DRG1; DKFZp434N1827; NEDD3

External IDs

OMIM: 603952 MGI: 1343297 HomoloGene: 3060

Gene ontology
Molecular Function:	• nucleotide binding • GTP binding • transcription factor binding
Cellular Component:	• intracellular
Biological Process:	• transcription • multicellular organismal development

Orthologs

Human

Mouse

Refseq

NM_004147 (mRNA)
NP_004138 (protein)

NM_007879 (mRNA)
NP_031905 (protein)

Location

Chr 22: 30.13 - 30.16 Mb

Chr 11: 3.15 - 3.17 Mb

Pubmed search

[1]

[2]

Developmentally regulated GTP binding protein 1, also known as DRG1, is a human gene.^[1]

[edit] References

^ Entrez Gene: DRG1 developmentally regulated GTP binding protein 1.

[edit] Further reading

Sazuka T, Kinoshita M, Tomooka Y, et al. (1992). "Expression of DRG during murine embryonic development.". Biochem. Biophys. Res. Commun. 189 (1): 371-7. PMID 1280421.
Sazuka T, Tomooka Y, Ikawa Y, et al. (1992). "DRG: a novel developmentally regulated GTP-binding protein.". Biochem. Biophys. Res. Commun. 189 (1): 363-70. PMID 1449490.
Schenker T, Lach C, Kessler B, et al. (1994). "A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts.". J. Biol. Chem. 269 (41): 25447-53. PMID 7929244.
Mahajan MA, Park ST, Sun XH (1996). "Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins.". Oncogene 12 (11): 2343-50. PMID 8649774.
Zhao XF, Aplan PD (1999). "SCL binds the human homologue of DRG in vivo.". Biochim. Biophys. Acta 1448 (1): 109-14. PMID 9824680.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489-95. doi:10.1038/990031. PMID 10591208.
Li B, Trueb B (2000). "DRG represents a family of two closely related GTP-binding proteins.". Biochim. Biophys. Acta 1491 (1-3): 196-204. PMID 10760581.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Bandyopadhyay S, Pai SK, Gross SC, et al. (2003). "The Drg-1 gene suppresses tumor metastasis in prostate cancer.". Cancer Res. 63 (8): 1731-6. PMID 12702552.
Bandyopadhyay S, Pai SK, Hirota S, et al. (2004). "Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression.". Oncogene 23 (33): 5675-81. doi:10.1038/sj.onc.1207734. PMID 15184886.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Bandyopadhyay S, Wang Y, Zhan R, et al. (2007). "The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.". Cancer Res. 66 (24): 11983-90. doi:10.1158/0008-5472.CAN-06-0943. PMID 17178897.