DPYSL5

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Dihydropyrimidinase-like 5
Identifiers
Symbol(s) DPYSL5; CRAM; CRMP-5; CRMP5; FLJ45383; Ulip6
External IDs OMIM: 608383 MGI: 1929772 HomoloGene: 41347
Orthologs
Human Mouse
Entrez 56896 65254
Ensembl ENSG00000157851 ENSMUSG00000029168
Uniprot Q9BPU6 Q9EQF6
Refseq NM_020134 (mRNA)
NP_064519 (protein)		 NM_023047 (mRNA)
NP_075534 (protein)
Location Chr 2: 26.92 - 27.03 Mb Chr 5: 30.99 - 31.08 Mb
Pubmed search [1] [2]

Dihydropyrimidinase-like 5, also known as DPYSL5, is a human gene.[1]

Members of the CRMP family, such as DPYSL5, are believed to play a role in growth cone guidance during neural development.[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: DPYSL5 dihydropyrimidinase-like 5.

[edit] Further reading

  • Cross SA, Salomao DR, Parisi JE, et al. (2003). "Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG.". Ann. Neurol. 54 (1): 38–50. doi:10.1002/ana.10587. PMID 12838519. 
  • Inatome R, Tsujimura T, Hitomi T, et al. (2000). "Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain.". J. Biol. Chem. 275 (35): 27291–302. doi:10.1074/jbc.M910126199. PMID 10851247. 
  • Fukada M, Watakabe I, Yuasa-Kawada J, et al. (2001). "Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.". J. Biol. Chem. 275 (48): 37957–65. doi:10.1074/jbc.M003277200. PMID 10956643. 
  • Horiuchi M, El Far O, Betz H (2000). "Ulip6, a novel unc-33 and dihydropyrimidinase related protein highly expressed in developing rat brain.". FEBS Lett. 480 (2-3): 283–6. PMID 11034345. 
  • Yu Z, Kryzer TJ, Griesmann GE, et al. (2001). "CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity.". Ann. Neurol. 49 (2): 146–54. PMID 11220734. 
  • Ricard D, Rogemond V, Charrier E, et al. (2001). "Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes.". J. Neurosci. 21 (18): 7203–14. PMID 11549731. 
  • Mitsui N, Inatome R, Takahashi S, et al. (2002). "Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling.". EMBO J. 21 (13): 3274–85. doi:10.1093/emboj/cdf328. PMID 12093729. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
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