Talk:Doxorubicin

From Wikipedia, the free encyclopedia

	Doxorubicin has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do. If it no longer meets these criteria, you can delist it, or ask for a reassessment.
May 10, 2007 Good article nominee Listed

This article was selected on the Medicine portal as one of Wikipedia's best articles related to Medicine.

This article is within the scope of the following WikiProjects:

WikiProject Pharmacology (Rated GA-Class) Doxorubicin is part of WikiProject Pharmacology, a project to improve all Pharmacology-related articles. If you would like to help improve this and other pharmacology articles, please join the project. All interested editors are welcome. GA This article has been rated as GA-Class on the quality scale. High This article has been rated as high-importance for this Project's importance scale. WikiProject Chemicals (Rated B-Class) Chemistry Portal Doxorubicin is within the scope of WikiProject Chemicals, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project. This article is also supported by WikiProject Chemistry. B This article has been rated as B-Class on the quality scale. Mid This article has been rated as mid-importance on the importance scale. Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need.

The cardiomyopathy of doxorubicin was reviewed in 1998: NEJM. JFW | T@lk 14:41, 22 December 2005 (UTC)

Contents 1 trade name 2 Passed GA 3 Skeletal formula 4 Automatic addition of "class=GA" 5 American Cancer Society Article Heart Problems

[edit] trade name

Adriamycin is a tradename and hence, should be spelled with a capital 'A'. Doxorubicin should not. —Preceding unsigned comment added by Kcoldie (talk • contribs)

I believe "Adriamycin" is still used as a genericized trademark in several countries when referring to doxorubicin. Go ahead and capitalize it if you feel it should be. Fvasconcellos 12:40, 24 November 2006 (UTC)

[edit] Passed GA

This looks good. Passes all criteria bar a couple of minor typos that it is easier to fix myself :) cheers, Cas Liber | talk | contribs 20:38, 10 May 2007 (UTC)

[edit] Skeletal formula

I just realized that the skeletal formula I'd added to the article was actually of epirubicin (which is an epimer of doxorubicin). PubChem doesn't make the distinction, and it took me nearly four months to notice :P I've fixed the image, and I apologize. Fvasconcellos (t·c) 22:10, 4 October 2007 (UTC)

Well, the first (upper) sceletal formula is of doxorubicin now, but the second one is wrong at all. The deficiencies are as follows: a) aromatical and aliphatical rings are shown in the same manner, b) the OH group in the hydroquinone ring is missed (upper), c)the H atom at the aglycone aliphatical cycle is in a wrong position, d) in the sugar moiety, the spacial positions of substituents are not clear. Was it necessary to add this formula to the article? --Nazar Saman (talk) 18:17, 1 June 2008 (UTC)

[edit] Automatic addition of "class=GA"

A bot has added class=GA to the WikiProject banners on this page, as it's listed as a good article. If you see a mistake, please revert, and leave a note on the bot's talk page. Thanks, _BOT Giggabot (talk) 05:24, 10 December 2007 (UTC)

[edit] American Cancer Society Article Heart Problems

I am adding this link as I found it very helpful to me and explains my 4 years of Chronic Fatigue and leg swelling heart palpitations and I have woken up my physicians do to this article from the American Cancer Society. I am now a 22 year survivor post 12 cycles of ABVD alternated with MOPP for Hodgkins Lymphoma (Adriamycin) is the A in ABVD. It is important to get your heart checked regularly even years after the drug therapy.

[1] —Preceding unsigned comment added by Nursemary56 (talk • contribs) 22:54, 22 March 2008 (UTC)

but the second one is wrong at all. The deficiencies are as follows: a) aromatical and aliphatical rings are shown in the same manner, b) the OH group in the hydroquinone ring is missed (upper), c)the H atom at the aglycone aliphatical cycle is in a wrong position, d) in the sugar moiety, the spacial positions of substituents are not clear. Was it necessary to add this formula to the article?

I have added {{Template:Disputed chem|the hydroquinone OH is missing, the sugar OH has the wrong stereochemistry}} to the image and removed it from the article. Cacycle (talk) 00:01, 2 June 2008 (UTC)